Publications

2016

  • Welch J, Liu Z, Wang L, Liu J, Lerou PH, Purvis JE, Qian L, Hartemink A, Prins J. SLICER: Inferring Branched, Nonlinear Cellular Trajectories from Single Cell RNA-seq Data. (2016) RECOMB 2016. (Also invited for submission to Cell Systems)
  • Lu J, Li H, Baccei A, Sasaki T, Gilbert DM, Lerou PHInfluence of ATM-mediated DNA damage response on genomic variation in human induced pluripotent stem cells. Stem Cells Dev. 2016 Mar 2. [Epub ahead of print] PMID: 26935587

2015

  • Walsh BH, Baumer FM, Bernson-Leung ME, Lerou PH, Peters JM. Teaching video neuroimages: nonepileptic myoclonus in a neonate following severe hypoxic-ischemic injury. Neurology. 2015, Mar 24;84(12):e90. PMID: 25802277
  • Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015 Oct 23;6:8715. PMID: 26493500

2014

  • Lu J, Li H, Hu M, Sasaki T, Baccei A, Gilbert DM, Liu JS, Collins JJ, Lerou PH. The distribution of genomic variations in human iPSCs is related to replication timing reorganization during reprogramming. Cell Reports. 2014 Mar 27. PMID: 24685138
  • Liu J, Lerou PH, Lahav G. Stem cell sensitivity and resistance to DNA damage. Trends in Cell Biology. PMID: 24721782
  • Zhao R, Deibler RW, Lerou PH, Ballabeni A, Heffner GC, Cahan P, Unternaehrer JJ, Kirschner MW, Daley GQ. A nontranscriptional role for Oct4 in the regulation of mitotic entry. Proc Natl Acad Sci USA. 2014 Nov 4;111(44):15768-73. PMID: 25324523
  • Gorman BR, Lu J, Baccei A, Lowry NC, Purvis JE, Mangoubi RS, Lerou, PH. Multi-Scale Imaging and Informatics Pipeline for In Situ Pluripotent Stem Cell Analysis. PLOS ONE. 2014, Dec 31;2014 Dec 31;9(12):e11603 PMID: 25551762

2013

  1. Cherry AB, Gagne KE, McLoughlin EM, Baccei A, Gorman B, Hartung O, Miller JD, Zhang J, Zon RL, Ince TA, Neufeld EJ, Lerou PH, Fleming MD, Daley GQ, Agarwal S. Induced pluripotent stem cells with a mitochondrial DNA deletion. Stem Cells. 2013;31:1287-1297. PMID: 23400930
  2. Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Letai A, Lerou PH*, Lahav G*. High mitochondrial priming sensitizes hESCs to DNA damage-induced apoptosis. Cell Stem Cell. 2013 Oct 7;13(4):483-91. PMID: 23954752
  3. Lam AQ, Freedman BS, Morizane R, Lerou PH, Valerius MT, Bonventre JV. Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm That Forms Tubules Expressing Kidney Proximal Tubular Markers. J Am Soc Nephrol. Epub 2013 Dec 19. PMID: 24357672

2012

  • Guan X, Yabuuchi A, Huo H, Ginsberg E, Racowsky C, Daley GQ, Lerou PH, Derivation of human embryonic stem cells with NEMO deficiency. Stem Cell Research. 2012;8(3):410-5. PMID: 22284529

2011

  • Ballabeni A, Park IH, Zhao R, Wang W, Lerou PH, Daley GQ, Kirschner MW. Cell cycle adaptations of embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(48):19252-19257. PMID: 22084091

2008

  • Lerou PH, Yabuuchi A, Huo H, Miller JD, Boyer LF, Schlaeger TM, Daley GQ. Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos. Nat Protoc. 2008;3(5):923-33. PMID: 18451800
  • Park IH, Lerou PH, Zhao R, Huo H, Daley GQ. Generation of human-induced pluripotent stem cells. Nat Protoc. 2008;3(7):1180-6. PMID: 18600223
  • Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ. Reprogramming of human somatic cells to pluripotency with defined factors. Nature. 2008 Jan 10;451(7175):141-6. Epub 2007 Dec 23. PMID: 18157115
  • Lerou PH, Yabuuchi A, Huo H, Takeuchi A, Shea J, Cimini T, Ince TA, Ginsburg E, Racowsky C, Daley GQ. Human embryonic stem cell derivation from poor-quality embryos. Nat Biotechnol. 2008;26(2):212-4. PMID: 18223642

2007

  • Kim K, Lerou PH, Yabuuchi A, Lengerke C, Ng K, West J, Kirby A, Daly MJ, Daley GQ. Histocompatible embryonic stem cells by parthenogenesis. Science. 2007;315(5811):482-6. PMID: 17170255
  • Lengerke C, Kim K, Lerou PH, Daley GQ. Differentiation potential of histocompatible parthenogenetic embryonic stem cells. Ann N Y Acad Sci. 2007;1106:209-18. PMID: 17360798